BrightFocus Foundation | October 29, 2019

Why One Researcher Fights to End Alzheimer鈥檚 Disease

Image caption: Yuriko and me together for a trip to a hot spring. She did not recognize me, but could speak.

Since 1985, BrightFocus Foundation鈥檚 has awarded more than $128 million for highly innovative science to end Alzheimer鈥檚. Right now, we are funding 105 research projects around the world, including an exciting study led by

Dr. Igarashi听saw first-hand how Alzheimer鈥檚 disease ravaged the brain of his late grandmother, Yuriko. Here is his story:

I started my career as a basic neuroscientist studying brain circuit mechanisms related to the sense of smell and then memory. While I was studying basic research during my PhD, my grandmother, Yuriko, started to show symptoms of Alzheimer鈥檚 disease. She was 78 at that time.

One day, she said 鈥業 put my purse here, but it鈥檚 gone! You stole my purse!鈥 Imagine how sad if your dearest grandma starts to doubt you. She was starting to lose her spatial memory and could not remember where she put her purse. We brought her to a doctor, even though she strongly refused. At that time, she was not diagnosed with Alzheimer鈥檚, but as we anticipated, she was diagnosed听a year later.

There were no drugs approved for Alzheimer鈥檚 disease in Japan at that time. All we could do for her is to have听fun together; to prevent her brain from worsening. We often brought her along for short trips.

These efforts were, however, in vain. She started to lose personal recognition at 84. I was one of the first听people she could not recognize. She called me 鈥榯eacher.鈥 鈥楬ello teacher, you have a beautiful baby,鈥 she said, when I visited her at her senior residence to show off my first baby. She loved my baby, but could not recognize that the baby was her first great-grandchild. I went out from the country to study more after that and was only able to visit听once a year. She started to use diapers.

Every time I visited her, she did not recognize me. I was asking myself,听鈥楢m I visiting her for her sake, or for my own sake?鈥 At 89, she lost recognition of my mother, her own daughter. Now she was all alone.

She passed away at 93. Alzheimer鈥檚 disease completely killed her personality, long before she passed away. I could not do anything for her, even though I AM A MEMORY RESEARCHER. This frustration keeps driving me to fight听Alzheimer鈥檚 disease.

You can help scientists, like Dr. Igarashi, find ways to better diagnose, prevent, and treat Alzheimer鈥檚 disease through a gift to Alzheimer鈥檚 Disease Research, a program of .

If you鈥檙e a military or federal employee, you can support Alzheimer鈥檚 Disease Research through the Combined Federal Campaign (CFC). Our CFC number is 30518.

If you鈥檙e a private sector employee, you can also help fund Alzheimer鈥檚 Disease Research through your employer鈥檚 workplace giving program.

Click here if your company would like to start a workplace giving program to support Alzheimer鈥檚 Disease Research. We have partnered with 糖心视频’s Charities, a workplace giving federation, which connects employees to the causes they care about the most.

Examples of what you and your employers鈥 donations to Alzheimer鈥檚 Disease Research can achieve听are listed below:

  • $5/week ($260/year) will purchase enough agarose, a powder used to make gel to isolate proteins, for several weeks in a biology lab. It could also purchase a vial of an antibody to detect tau in animal models of Alzheimer鈥檚.
  • $20/week ($1,040/year) will cover the cost of an experiment to measure Alzheimer鈥檚 biomarkers (signs) in blood samples.
  • $20 – $40/week ($1,000 – $2,000/year) helps send a promising young researcher to an international science conference to share research results – a critical venue for analysis of discoveries.
  • $100 – $200/week ($5,200 – $10,400/year) can fund BrightFocus Foundation鈥檚 Resource Center, which develops and distributes free publications and resources, and serves as a liaison between people living with Alzheimer鈥檚 disease, medical professionals, health organizations, and government agencies.

To learn more about the research that you can help support, visit .

Support BrightFocus Foundation’s Alzheimer’s Disease Research program听through your employee giving听program:

As a donor, you can support BrightFocus Foundation by听donating to them through your employer鈥檚 workplace giving program听(颁贵颁#30518if you’re a military or federal employee participating in the Combined Federal Campaign).听Payroll pledges made through employer-sponsored charitable giving programs represent a听cost effective and near effortless way to support your favorite charities.

As BrightFocus Foundation’s听workplace giving partner, 糖心视频鈥檚 Charities can help your company design and implement a program centered on supporting their work – through workplace giving campaigns, employee fundraising, cause-focused signature programs, volunteerism, donation drives, matching gifts, Dollars-for-Doers, In-Kind Giving and other employee engagement and philanthropic initiatives.听Click here听to request a demo and learn how we can help you do this.

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